MRI acquisition protocol

The scanning sequences required for Omniscient software include a 3D T1 weighted scan, an advanced diffusion (DTI) sequence, and a resting-state fMRI. The exact sequence names and parameters will depend on the MRI model and software version which is covered further in our Detailed MRI Acquisition Guide.  

Feature Requirement / Standard
MRI manufacturer GE, Siemens, Philips, Canon, and other major MRI manufacturers
Field strength 1.5T or 3.0T
Scan protocol 3D T1 TFE, DTI and resting state fMRI
Patient instructions
  • Minimize head motion
  • Do not think of anything
  • Keep eyes open and do not fall asleep
  • Do not use headphones or other audio devices during scan
Technician instructions
  • Ensure head alignment during localizer
  • Do not compress anatomy/fiducials with padding; no anaesthesia masks
  • Do not place tape on the forehead
DTI sequence
  • One b0 baseline image
  • B1000
  • At least 30 and ideally 50-60 directions+ one baseline b0 scan
  • FOV=25.6 cm
  • Slice thickness 2mm
  • 0 mm gap between slices with no overlap
  • Full brain coverage
  • Isotropic voxels
  • Square 128x128 matrix
  • 1 average/NEX
  • Axial foot to head slice prescription
  • DTI done before contrast images
Resting state fMRI sequence
  • 3 × 3 × 3-mm voxels
  • 128 volumes/run
  • TE = 27 ms
  • TR = 2.8 s
  • Field of view = 256 mm
  • Flip angle = 90˚
  • Run time about 8 min

This product is not a medical device. It is not intended for use in the diagnosis of disease or other conditions, or in the cure, mitigation, treatment, or prevention of disease. This product is to be used for research only.